Welcome to the SIREN Study Portal

SIREN (Sarscov2 Immunity & REinfection EvaluatioN): The impact of detectable anti SARS-COV2 antibody on the incidence of COVID-19 in healthcare workers


Thank you very much for your interest in joining SIREN. Unfortunately, recruitment finished on 31st March 2021 and we are no longer accepting new participants.

We thank all participants for their support.

Existing participants

Get in touch

If you have further questions and would like to get in touch with the study team, please contact your organisation’s research team or email us at: phe.siren.participants@phe.gov.uk.

Update my details or withdraw from the study

To update your contact details or contact preferences, or withdraw from the study: click here.

What is the SIREN study?

The purpose of this study is to understand whether prior infection with SARS-CoV2 (the virus that causes COVID-19) protects against future infection with the same virus.

The study has received approval from the NHS Health Research Authority Berkshire Research Ethics Committee and is funded by the National Institute of Health Research and Public Health England.

You can get further information about this study by speaking to your organisation's research team or by looking at the Participant Information Leaflet.

There is also further information available for participants in the following resources: